Please note that these resources have not all been tested in schools. We would greatly appreciate any feedback on the resources (good or otherwise!), and encourage you to submit feedback via our online form here.
Many of the interactive resources use the software PyMOL to manipulate real structures and explore scientific principles. To make this process easier, we have prepared a selection of structures for you to use and explore. Any of these structures which are used as part of our worksheet activities will be available to download next to the worksheet on our resources pages.
Although we have pre-selected some structures for you to explore, you can access any of the 130,000+ entries available on the PDBe website, simply by searching for the protein that you are interested in at: www.ebi.ac.uk/pdbe. Then, once you have chosen a structure, type the unique 4-character code in the form 'fetch ****' into PyMOL.
Some of these files are provided with in-built animations, and they are all free for you to explore. To make sure that you feel confident in using PyMOL to explore biochemical structures, please view our guides on the Introductory Resources page. If you have any suggestions for proteins or structures which you would like us to include then please let us know on our Contact page.
Many of the interactive resources use the software PyMOL to manipulate real structures and explore scientific principles. To make this process easier, we have prepared a selection of structures for you to use and explore. Any of these structures which are used as part of our worksheet activities will be available to download next to the worksheet on our resources pages.
Although we have pre-selected some structures for you to explore, you can access any of the 130,000+ entries available on the PDBe website, simply by searching for the protein that you are interested in at: www.ebi.ac.uk/pdbe. Then, once you have chosen a structure, type the unique 4-character code in the form 'fetch ****' into PyMOL.
Some of these files are provided with in-built animations, and they are all free for you to explore. To make sure that you feel confident in using PyMOL to explore biochemical structures, please view our guides on the Introductory Resources page. If you have any suggestions for proteins or structures which you would like us to include then please let us know on our Contact page.
PyMOL Files |
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1a84_Cisplatin_2 Example of cisplatin disrupting the structure of a DNA double helix
download here: 1a84_cisplatin_2.pse
1enn_DNA Example of a DNA double helix
download here: 1enn_dna.pse
1enn_DNA_Base_Pairs Example of the base pairing between DNA strands
download here: 1enn_dna_base_pairs.pse
1qho_Amylase_Active_Site Example of sugars bound to the enzyme amylase
download here: 1qho_amylase_active_site.pse
1tup_Tumour_Suppressor_Protein Example of a protein-DNA complex. The tumour suppressor protein helps to regulate DNA replication, and mutations in this protein can lead to various cancers forming
download here: 1tup_tumour_suppressor_protein.pse
1tyn_Inhibitor_Mutated Example of a mutation occurring on an enzyme. Shows how mutations may not always effect the ability of the enzyme
download here: 1tyn_inhibitor_mutated.pse
2pgz_Cocaine Example of cocaine bound to an acetylcholine receptor
download here: 2pgz_cocaine.pse
3u8r_Thrombin_Multiple_Active_Sites Example of a human thrombin protein, with multiple ligands attached
download here: 3u8r_thrombin_multiple_active_sites.pse
3ufy_3r58_Naproxen_Enantiomers Example of two naproxen enantiomes bound to a protein
download here: 3ufy_3r58_naproxen_enantiomers.pse
4yx4_Carbonic_Anhydrase_Inhibitor Example of the enzyme carbonic anhydrase bound to an inhibitor
download here: 4yx4_carbonic_anhydrase_inhibitor.pse
PyMOL Animation Files |
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